Photoacoustic microscopy by scanning mirror-based synthetic aperture focusing technique
نویسندگان
چکیده
Photoacoustic imaging with a synthetic aperture focusing technique (SAFT) is an effective method to improve the lateral resolution for out-of-focus regions in scanning microscopy systems, which commonly require a decent motorized scanning stage for a lateral scan of a transducer to obtain a cross-sectional image. In this study, we propose and test a photoacoustic imaging system with a scanning mirror-based SAFT (SM-SAFT) for simple and fast data acquisition, without the need for a physical scan of the transducer. Photoacoustic images of hair phantoms acquired by SM-SAFT are demonstrated, serving as a proof-of-concept experiment to show the feasibility and potential of the proposed approach. OCIS codes: 110.5120, 180.5810, 110.6880. doi: 10.3788/COL201513.101101.
منابع مشابه
In vivo volumetric imaging of subcutaneous microvasculature by photoacoustic microscopy.
Photoacoustic microscopy was developed to achieve volumetric imaging of the anatomy and functions of the subcutaneous microvasculature in both small animals and humans in vivo with high spatial resolution and high signal-to-background ratio. By following the skin contour in raster scanning, the ultrasonic transducer maintains focusing in the region of interest. Furthermore, off-focus lateral re...
متن کاملPhotoacoustic microscopy in vivo using synthetic-aperture focusing technique combined with three-dimensional deconvolution.
Acoustic-resolution photoacoustic microscopy (ARPAM) plays an important role in studying the microcirculation system of biological tissues with deep penetration. High lateral resolution of ARPAM is achieved by using a high numerical aperture acoustic transducer. The deteriorated lateral resolution in the out-of-focus region can be alleviated by synthetic aperture focusing technique (SAFT). Prev...
متن کاملImproved in vivo photoacoustic microscopy based on a virtual-detector concept.
Recently an in vivo high-resolution backward-mode photoacoustic microscope was developed that shows potential for applications in dermatology and related cancer research. However, the limited depth of focus of the large-numerical-aperture (NA) ultrasonic lens employed in this system causes the image quality to deteriorate significantly in the out-of-focus region. To solve this problem, we devis...
متن کاملRemote Contactless Photoacoustic Imaging for Non Destructive Testing
We report on (to our knowledge) the first remote contactless photoacoustic measurements on semitransparent polymer samples. Samples consisting of a semitransparent polymer surface, black silicon glue and cast resin were produced. Measurements were done by illuminating the samples with short electromagnetic pulses of infrared radiation and detecting the generated ultrasound waves with a Fabry-Pé...
متن کاملFourier Domain Reconstruction Methods in Laser Ultrasonics and Photoacoustic Imaging
Laser-ultrasonics as well as photoacoustic imaging use optically generated acoustic waves detected at the sample surface to image its interior. In laser-ultrasonics, a laser pulse is absorbed at the sample surface generating an ultrasound pulse that propagates into the sample, is reflected at internal structures, and is detected at the surface. In photoacoustic imaging, the source of the ultras...
متن کامل